Please use this identifier to cite or link to this item: https://hdl.handle.net/11000/6984
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dc.contributor.authorChico, Verónica-
dc.contributor.authorNombela Díaz, Iván-
dc.contributor.authorPuente Marín, Sara-
dc.contributor.authorOrtega-Villaizan Romo, María del Mar-
dc.date.accessioned2021-01-25T09:06:57Z-
dc.date.available2021-01-25T09:06:57Z-
dc.date.created2018-07-27-
dc.date.issued2021-01-25-
dc.identifier.isbn978-1-78985-152-6-
dc.identifier.urihttp://hdl.handle.net/11000/6984-
dc.description.abstractIt has recently come to light that nucleated red blood cells (RBCs) of fish, amphibians, reptiles and birds are multifunctional cells, because in addition to being involved in gas exchange and transport, it has also been reported that they respond to pathogens by means of (i) phagocytosis, (ii) antigen presentation, (iii) production of cytokines and antimicrobial peptides, (iv) regulation of complement system, and (v) exerting paracrine molecular communication with other immune cells and modulating their functions. Similarly, human cord blood nucleated RBCs have been shown to exert a regulatory function in the innate immune response, by means of the suppression of the production of inflammatory cytokines. This chapter comprises the study of the implications of nucleated RBCs as mediators of both branches of immune system (innate and adaptive immune responses).es
dc.description.sponsorshipThis work was supported by the European Research Council (ERC Starting Grant GA639249)-
dc.formatapplication/pdfes
dc.format.extent15es
dc.language.isoenges
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectnucleated red blood cellses
dc.subjecterythrocyteses
dc.subjectimmune responsees
dc.subjectcytokineses
dc.subjectantimicrobial peptideses
dc.subjectviruses
dc.subjectantigen presentationes
dc.subject.other577 - Bioquímica. Biología molecular. Biofísicaes
dc.titleNucleated Red Blood Cells Contribute to the Host Immune Response Against Pathogenses
dc.typeinfo:eu-repo/semantics/articlees
dc.contributor.instituteInstituto de Biología Molecular y Celulares
dc.identifier.doi10.5772/intechopen.80545-
dc.relation.publisherversionhttps://doi.org/ 10.5772/intechopen.80545-
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